General Cell Lines and Cell Cultures
Lonza Walkersville P4 PC 384-well Nufe Kit L
The P4 Primary Cell 384-well Nucleofector Kit is one of our five kits suited for high-throughput transfection of primary cells when working with the 384-well HT Nucleofector System This kit has been determined to be optimal for transfecting following cell types B cell (mouse) DC (mouse) immat MEF (mouse) The respective cell type-specific Optimized Protocols or recommendations are available under Instructions or in our Lonza Bioscience knowledge database In these Optimized Protocols the best Nucleofection conditions are indicated In addition we share our experience and knowledge for treatment of individual cell types The kit is available in different variants for either 2 x 384 or 10 x 384 reactions
Eurofins Discoverx PathHunter U2OS mCXCR7 β-Arrestin Cell Line, 2 vials. (93-0689C3)
The PathHunter mCXCR7 (mCMKOR1) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CXCL12/SDF-1α) based activation of mCXCR7 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCXCR7 and EA-tagged β-Arrestin-2. Activation of mCXCR7 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Genscript Corporation CHO-K1/4-1BB Stable Cell Line
Recombinant CHO-K1 cells stably overexpress human TNF receptor superfamily member 9 (4-1BB) on the surface The surface expression of 4-1BB is validated by FACS analysis
Eurofins Discoverx PathHunter HEK 293 EDG3 β-Arrestin Cell Line, 2 vials. (93-0217C1)
The PathHunter EDG3 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. S1P) based activation of EDG3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged EDG3 and EA-tagged β-Arrestin-2. Activation of EDG3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the cynomolgus version of the protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
STEMCELL Technologies Human Whole Peripheral Blood Collected with ACDA, Fresh, Size: 200 mL
Normal whole peripheral blood (PB) is obtained from healthy donors using Institutional Review Board (IRB)-approved consent forms and protocols. Acid citrate dextrose, solution A (ACDA), Sodium Heparin (Na-Hep), Ethylenediaminetetraacetic acid (EDTA), or Citrate-phosphate-double-dextrose (CP2D) is the anticoagulant.Certain products are only available in select territories. Please contact your local Sales representative or Product & Scientific Support at techsupport@stemcell.com for further information and to inquire about donor selection or information including BMI category, smoking status, ethnicity, etc.Browse our Frequently Asked Questions (FAQs) (https://www.stemcell.com/primary-cells-faq) on Primary Cells.
Eurofins Discoverx PathHunter U2OS EphA4 Functional Assay, 2 vials. (93-0877C3)
The PathHunter U2OS EphA4 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated EphA4 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged EphA4 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
Promocell GmbH PromoCell NHEK-c 500,000 Human Epidermal Keratinocytes, pooled, adult, cryopreserved
Primary Normal Human Epidermal Keratinocytes (NHEK) are available from single or from pooled donors isolated from the epidermis of juvenile foreskin or adult skin from different locations like the face, the breasts, the abdomen, and the thighs. They are the major cell type in the epidermis, making up about 90% of the cells.Epidermal keratinocytes originate in the stratum basale and move up through the layers of the epidermis. During this movement, they undergo gradual differentiation and morphology changes until they reach the stratum corneum, where they form a layer of nucleus-free, flat, and highly keratinized squamous cells. This layer forms an effective barrier to the entry of infectious agents into the body and minimizes moisture loss.Keratinocytes are also able to produce a variety of cytokines, growth factors, interleukins and complement factors. Therefore keratinocytes are important for wound healing, inflammation, and immune response.
ATCC Hepa 1-6; Hepatoma; Mouse (Mus musculus)
There is a Permit requirement: License form needed to be completed Material Transfer Agreement Addendum for Screening Application
The forms are available here: https://www.atcc.org/support/order-support/permits-and-restrictions
ATCC pfizer Pneumococcal polysaccharide powder Type 14 (d14) 2mg
Purified pneumococcal polysaccharide type 14 is manufactured by Pfizer, Inc. for small quantity distribution by ATCC. The pneumococcal powder type 14 is a component of the current 13-valent vaccine against Streptococcus pneumoniae. The pneumococcal polysaccharide type 14 can be used to assay for type-specific antibodies, research immune responses and study immunodeficiencies.
Cell Applications Inc Cryopreserved Colonic Epithelial Cells (HCnEpC), fetal
Cryopreserved Colonic Epithelial Cells (HCnEpC), fetal
STEMCELL Technologies Human Peripheral Blood Th17 Cells, Frozen, Size: 2 x 10^6 cells
Primary human cells, frozen
Biochain Institute Inc Matched Pair - DNA - Human Primary Tumor and Normal Tissue: Colon, 2x10 ug/PK
BioChain's human DNA matched pair products include: Primary Pair (PP), Primary and Metastasis Pair (PM). PP consists of DNA prepared from primary tumor and its adjacent normal tissue; PM consists of DNA prepared from primary tumor and corresponding ponding metastatic tumor. Genomic DNA in each pair is prepared from the same donor. This product line is designed foridentifying tumor-specific genes and tumor metastatic genes.
ABclonal Technology Dopamine Receptor D3 (DRD3) Rabbit pAb
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).